purine metabolism

The end product of purine metabolism varies from species to species .

嘌呤代谢是动物含氮废物排出体外的重要途径之一。

Purine metabolism in Schistosoma japonicum

日本血吸虫嘌呤代谢的研究

Uric acid as the end-product of purine metabolism in human body is excreted through kidney .

尿酸是人体嘌呤碱基分解代谢终产物，经肾脏排泄。

Background . Uric acid is the product of purine metabolism ; however , a relatively higher level of serum uric acid in human is observed than that in other mammals since genetic mutations .

背景尿酸是嘌呤代谢产物，人类进化过程中尿酸酶基因突变，使人的血尿酸水平较其它哺乳动物高。

Most prokaryote and eukaryote have intact urate oxidase gene ( wo ) that produces urate oxidase activity and excretes allantoin as the end product of purine metabolism .

大多数的原核和真核生物都有完整的尿酸氧化酶基因，产生具生物活性的尿酸氧化酶，以尿囊酸作为代谢最终产物。

Urate oxidase has been found in the body of many species , while birds and some higher primates ( eg apes and humans ) lack functional urate oxidase in vivo and excrete uric acid as the end product of purine metabolism .

在许多物种体内均发现有尿酸氧化酶，但在鸟类及一些高等灵长类动物（如猿和人类）的体内却缺乏具有功能的尿酸酶，而是以尿酸作为嘌呤代谢的终产物排出体外。

Human beings lack active uricase because of gene mutations , leading to uric acid as the end product of purine metabolism and resulting in the development of urate nephropathy and gouty arthritis when the concentration of uric acid reaches its solubility limit in blood ( hyperuricemia ) .

人类由于基因突变而缺乏活性尿酸酶，这导致人类以尿酸作为嘌呤代谢的终产物。当人血液中尿酸浓度高于其溶解度（高尿酸血症）时可引起尿酸性肾病和痛风性关节炎。

Effects of High Intensity Exercise on Purine Nucleotide Metabolism of Rats And Study of Motor Model

大强度运动对大鼠嘌呤核苷酸代谢的影响及运动模型研究

Effect of morphine on purine nucleotides metabolism in gene level

吗啡在基因水平对脑嘌呤核苷酸代谢的影响

The effects of high intensity exercise on purine nucleotide metabolism of rats were studied in this paper . Simultaneously , the feasibility of the motor model was discussed .

观察大强度运动对大鼠嘌呤核苷酸代谢的影响，同时分析所建运动模型的可行性。

Conclusion Morphine may affect purine nucleotide metabolism of nerve cells , increase the adenylate and adenosine levels , which may be one of the mechanism of morphine dependence and tolerance .

结论：吗啡影响神经细胞嘌呤核苷酸代谢，使细胞内腺苷酸及腺苷水平增高，这可能是吗啡依赖和耐受形成的机理之一。

Objective : To observe the changes of purine nucleotide metabolism of rat central nervous system during morphine dependence and withdrawal , and look for regulating and domino effect related to morphine dependence .

目的：通过研究吗啡对大鼠脑组织嘌呤核苷酸代谢的影响，寻找吗啡依赖相关的调控与效应基因。

Free radicals were produced in the process of arachidonic acid metabolism , adenosine purine nucleotide metabolism and nitric oxide pathway after cerebral ischemia and reperfusion , which may be an important mechanism of BBB permeability alteration .

脑缺血及其再灌注后可通过花生四烯酸代谢途径、嘌呤核苷酸代谢途径及一氧化氮途径产生自由基，可能是血脑屏障通透性增加的重要机制。

Purine and lipid metabolism are important in diabetes patients and are more helpful for physician to evaluate coronary artery risk .

综合考虑患者体内的嘌呤代谢和脂质代谢，尤其对于糖尿病患者更为重要，也更有利于临床医师合理评价冠状动脉风险。

These genes involved in ribosome , photosynthesis , oxidative phosphorylation , purine and pyrimidine metabolism and chlorophyll biosynthesis .

Pathway分析发现这些差异基因涉及最多的是核糖体、光合作用、氧化磷酸化、嘌呤嘧啶代谢和叶绿素合成途径中。

Uric acid ( UA ) is an end product from purine derivatives in human metabolism .

尿酸是嘌呤的最终代谢产物。

With the increase in people purine diet , the body of purine metabolism disorder , and ultimately cause hyperuricemia , gout and hyperuricemia is an important prerequisite for the onset .

随着人们嘌呤饮食增多，体内嘌呤代谢的发生紊乱，最终引起高尿酸血症，而且高尿酸血症是痛风发病的重要前提。